In her role as Research Director for the CAS GMSA, Sarah facilitates clinical research pathways to optimise use and analysis patient genomic data for better health outcomes. In her academic role Sarah is Professor of Genomics at the University of Southampton. She has worked in the field of genetic epidemiology for over 20 years and runs the Human Genomic Informatics Group dry laboratory, specialising in the analysis of large-scale genomic data in clinical cohorts. She has published around 180 papers with focus on underpinning the molecular genetic basis of human rare and common disease. Sarah is chief investigator of cohort studies recruiting NHS patients and leads projects analysing Genomics England and UKBioBank data. Projects include optimisation and cleaning of digitally extracted NHS data, execution of contemporary sequencing of DNA and RNA from patient samples and integration of data from multiple ‘omic sources using machine learning approaches to inform clinical management.